UBA5

Across TCGA cell cohorts, UBA5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,277 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBA5-associated GO terms across cancer lineages are Double-strand break repair via nonhomologous end joining, Mitochondrial tRNA wobble uridine modification, and Protein localization to chromosome. Each is linked with UBA5 in more than 13 cancer types. Because this analysis shows association rather than direction, both UBA5-to-partner and partner-to-UBA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Double-strand break repair via nonhomologous end joining grouped by UBA5-low versus UBA5-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBA5→partner) and Y-score (partner→UBA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Double-strand break repair via nonhomologous end joining →	+0.085	+0.811	<.001	.006	3	14
LIVER	Mitochondrial tRNA wobble uridine modification →	+0.154	+0.803	.004	<.001	3	13
BONE	Protein localization to chromosome →	+0.089	+0.525	<.001	.002	3	13
BONE	Microtubule nucleation →	+0.116	+0.599	.001	.004	3	13
SOFT_TISSUE	Regulation of cell fate commitment →	+0.153	+0.803	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of calcium ion export across plasma membrane →	+0.092	+0.756	.002	.003	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,277 associations by consensus.

Double-strand break repair via nonhomologous end joining by UBA5 expression — OESOPHAGUS

Explore this box plot interactively →