UBA2

Across TCGA patient cohorts, UBA2 protein abundance is significantly associated with the RNA expression of many other genes, with 19,736 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UBA2-associated genes across cancer lineages are ZNF227, LSM14A, and GPATCH1. Each is linked with UBA2 in more than 7 cancer types. Because this analysis shows association rather than direction, both UBA2-to-partner and partner-to-UBA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBA2 versus ZNF227 in OV, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBA2→partner) and Y-score (partner→UBA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZNF227 →	+0.725	+0.340	<.001	<.001	3	8
HNSC	LSM14A →	+0.871	+0.336	<.001	<.001	3	8
OV	GPATCH1 →	+0.768	+0.353	<.001	<.001	3	8
HNSC	ANKRD27 →	+0.754	+0.332	<.001	<.001	3	7
UCEC	NCF2 →	-1.251	-0.227	<.001	<.001	3	7
OV	CEP89 →	+0.838	+0.345	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,736 associations by consensus.

UBA2 vs ZNF227 — OV

Explore this scatter interactively →