Across TCGA patient cohorts, UAP1L1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,233 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible UAP1L1-associated genes across cancer lineages are GPNMB, RIN3, and SIGLEC8. Each is linked with UAP1L1 in more than 4 cancer types. Because this analysis shows association rather than direction, both UAP1L1-to-partner and partner-to-UAP1L1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UAP1L1→partner) and Y-score (partner→UAP1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GPNMB →	+1.361	+0.395	<.001	<.001	3	5
OV	RIN3 →	+0.723	+0.425	.003	<.001	3	4
BRCA	SIGLEC8 →	+0.930	+0.337	<.001	<.001	3	4
BRCA	ECM2 →	+0.951	+0.291	<.001	<.001	3	4
OV	ENG →	+1.055	+0.358	<.001	<.001	3	4
OV	DUSP3 →	+0.539	+0.354	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,233 associations by consensus.

Exploration

UAP1L1 survival (RNA) · tumor vs normal (RNA) · all UAP1L1 data types