Across TCGA cell cohorts, UAP1L1 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UAP1L1-associated genes across cancer lineages are ZNF804B, KHDRBS2, and PABPC1L2B. Each is linked with UAP1L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UAP1L1-to-partner and partner-to-UAP1L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UAP1L1→partner) and Y-score (partner→UAP1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	ZNF804B →	+0.033	+4.472	<.001	.004	3	2
OESOPHAGUS	KHDRBS2 →	+0.603	+4.906	<.001	.006	3	1
UPPER_AERODIGESTIVE_TRACT	PABPC1L2B →	+0.099	+4.736	.009	.009	3	1
LARGE_INTESTINE	TKTL2 →	+0.059	+4.509	<.001	<.001	3	1
LARGE_INTESTINE	MSGN1 →	+0.056	+3.345	.007	.007	3	1
LARGE_INTESTINE	TFDP3 →	+0.020	+3.196	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

UAP1L1 survival (RNA) · tumor vs normal (RNA) · all UAP1L1 data types