U2AF2

RNA expression — cross-omics
Cross-omicsRNA → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, U2AF2 RNA expression is significantly associated with the RNA expression of many other genes, with 11,200 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible U2AF2-associated genes across cancer lineages are HNRNPUL1, PRPF31, and HSPBP1. Each is linked with U2AF2 in more than 19 cancer types. Because this analysis shows association rather than direction, both U2AF2-to-partner and partner-to-U2AF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, U2AF2 versus HNRNPUL1 in URINARY_TRACT, with a Pearson correlation of 0.77.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (U2AF2→partner) and Y-score (partner→U2AF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTHNRNPUL1 →+1.318+1.293<.001<.001320
BLOOD_MyelomaPRPF31 →+1.162+1.103<.001<.001320
BLOOD_MyelomaHSPBP1 →+1.629+1.107<.001<.001320
BLOOD_LymphomaHNRNPL →+0.999+1.207<.001<.001319
BLOOD_LymphomaTARDBP →+0.770+1.025<.001<.001319
BLOOD_LymphomaTRIM28 →+0.980+1.141<.001<.001319
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,200 associations by consensus.

U2AF2 vs HNRNPUL1 — URINARY_TRACT

Per-sample scatter of U2AF2 vs HNRNPUL1 in URINARY_TRACT (Pearson r = 0.77).

Explore this scatter interactively →

Exploration