TYW5

Across TCGA pan-cancer cohorts, TYW5 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TYW5 data layer compared with 23 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher TYW5 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TYW5 expression acts as an unfavorable survival marker.

PDAC, CCRCC, and LUAD are the cancer types where TYW5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	All	0.243	0.447	.014	19	view →
CCRCC	DFS	Median	II,III,IV	0.464	0.753	.021	3	view →
LUAD	OS	Median	III,IV	0.803	0.949	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TYW5–PDAC (DFS)

Open the PDAC breakdown →