TYW5

Across TCGA patient cohorts, TYW5 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,411 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TYW5-associated proteins across cancer lineages are U2AF2, SF3B3, and SRSF7. Each is linked with TYW5 in more than 4 cancer types. Because this analysis shows association rather than direction, both TYW5-to-partner and partner-to-TYW5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TYW5 versus U2AF2 in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TYW5→partner) and Y-score (partner→TYW5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	U2AF2 →	+0.208	+0.479	<.001	<.001	3	5
GBM	SF3B3 →	+0.178	+0.202	<.001	.005	3	5
GBM	SRSF7 →	+0.338	+0.436	<.001	<.001	3	5
GBM	HNRNPA3 →	+0.176	+0.297	.001	.001	3	5
LSCC	AQR →	+0.221	+0.331	<.001	<.001	3	5
HNSC	NELFCD →	+0.369	+0.494	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,411 associations by consensus.

TYW5 vs U2AF2 — LSCC

Explore this scatter interactively →