TYW5

Across TCGA patient cohorts, TYW5 protein abundance is significantly associated with the RNA expression of many other genes, with 4,783 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TYW5-associated genes across cancer lineages are NIF3L1, CALCOCO1, and IL11RA. Each is linked with TYW5 in more than 3 cancer types. Because this analysis shows association rather than direction, both TYW5-to-partner and partner-to-TYW5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TYW5 versus NIF3L1 in LSCC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TYW5→partner) and Y-score (partner→TYW5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NIF3L1 →	+0.615	+0.237	<.001	<.001	3	4
HNSC	CALCOCO1 →	-0.338	-0.195	.006	.003	3	3
HNSC	IL11RA →	-0.858	-0.297	<.001	<.001	3	3
UCEC	OGN →	-0.819	-0.154	<.001	.002	3	3
LSCC	COQ10B →	+0.372	+0.197	.003	.005	3	3
LSCC	HDLBP →	+0.374	+0.209	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,783 associations by consensus.

TYW5 vs NIF3L1 — LSCC

Explore this scatter interactively →