TYW5

Across TCGA cell cohorts, TYW5 protein abundance is significantly associated with the RNA expression of many other genes, with 2,611 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible TYW5-associated genes across cancer lineages are SUCLA2, AKAP11, and ERLIN1. Each is linked with TYW5 in more than 5 cancer types. Because this analysis shows association rather than direction, both TYW5-to-partner and partner-to-TYW5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TYW5 versus SUCLA2 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TYW5→partner) and Y-score (partner→TYW5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	SUCLA2 →	+1.005	+1.150	<.001	.002	3	6
UPPER_AERODIGESTIVE_TRACT	AKAP11 →	+0.918	+0.988	<.001	.001	3	6
LIVER	ERLIN1 →	+0.745	+0.651	.003	.004	3	5
BREAST	PSMC3IP →	+1.046	+0.905	.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	SLC4A1AP →	+0.452	+0.989	.007	.001	3	5
OVARY	TBC1D1 →	+0.671	+0.819	.002	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,611 associations by consensus.

TYW5 vs SUCLA2 — UPPER_AERODIGESTIVE_TRACT

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