TYSND1

Across TCGA patient cohorts, TYSND1 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TYSND1-associated genes across cancer lineages are CD8+ naive T-cells and Class-switched memory B-cells. Each is linked with TYSND1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TYSND1-to-partner and partner-to-TYSND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ naive T-cells grouped by TYSND1-low versus TYSND1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TYSND1→partner) and Y-score (partner→TYSND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ naive T-cells →	+0.048	+3.016	<.001	.019	3	1
UCEC	Class-switched memory B-cells →	-0.059	-3.321	.048	.010	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD8+ naive T-cells by TYSND1 expression — UCEC

Explore this box plot interactively →