TYSND1

Across TCGA cell cohorts, TYSND1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,784 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TYSND1-associated GO terms across cancer lineages are Viral translational termination-reinitiation, Pre-mRNA catabolic process, and Base-excision repair, gap-filling. Each is linked with TYSND1 in more than 11 cancer types. Because this analysis shows association rather than direction, both TYSND1-to-partner and partner-to-TYSND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral translational termination-reinitiation grouped by TYSND1-low versus TYSND1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TYSND1→partner) and Y-score (partner→TYSND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.093	+0.837	<.001	<.001	3	12
BONE	Pre-mRNA catabolic process →	+0.152	+1.015	.002	.009	3	12
STOMACH	Base-excision repair, gap-filling →	+0.120	+1.403	.001	<.001	3	11
URINARY_TRACT	Actin-myosin filament sliding →	-0.267	-1.410	.004	<.001	3	10
LUNG_NSCLC_LUSC	UV-damage excision repair →	+0.086	+0.725	.004	.008	2	11
BLOOD_Lymphoma	Positive regulation of isotype switching to IgG isotypes →	+0.145	+0.971	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,784 associations by consensus.

Viral translational termination-reinitiation by TYSND1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →