TYRL

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TYRL RNA expression is significantly associated with the go_rna of many other GO terms, with 5,851 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TYRL-associated GO terms across cancer lineages are Membrane lipid biosynthetic process, Organic acid catabolic process, and Circadian rhythm. Each is linked with TYRL in more than 4 cancer types. Because this analysis shows association rather than direction, both TYRL-to-partner and partner-to-TYRL results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TYRL→partner) and Y-score (partner→TYRL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADMembrane lipid biosynthetic process →+0.088+0.055<.001<.00135
STADOrganic acid catabolic process →+0.082+0.049<.001<.00134
STADCircadian rhythm →+0.089+0.075<.001<.00134
STADRegulation of lysosomal lumen pH →+0.114+0.046<.001<.00134
STADCristae formation →+0.106+0.045<.001<.00134
STADMitochondrial electron transport, succinate to ubiquinone →+0.083+0.045<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,851 associations by consensus.

Exploration