TYMP

Across TCGA pan-cancer cohorts, TYMP Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated TYMP data layer compared with 22 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher TYMP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TYMP expression acts as an unfavorable survival marker.

BLCA, THCA, and UCEC are the cancer types where TYMP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	III,IV	0.051	0.684	<.001	24	view →
THCA	DFS	Median	All	0.070	0.896	<.001	18	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
LGG	DFS	Median	All	0.110	0.833	<.001	6	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →
LUAD	OS	Median	All	0.241	0.684	.037	3	view →
COAD	OS	Median	All	0.603	0.872	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

TYMP–BLCA (OS)

Open the BLCA breakdown →