TYMP

Across TCGA pan-cancer cohorts, TYMP mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TYMP data layer compared with 22 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TYMP mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TYMP expression acts as an unfavorable survival marker.

COAD, GBM, and HNSC are the cancer types where TYMP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Quartile	II,III,IV	0.791	1.000	.010	84	view →
GBM	OS	Quartile	All	0.229	0.665	.002	13	view →
HNSC	OS	Median	III,IV	0.529	0.782	.013	8	view →
LUAD	OS	Median	II,III,IV	0.420	0.771	.009	8	view →
CCRCC	OS	Median	All	0.911	1.000	.023	4	view →
LSCC	OS	Median	II,III,IV	0.623	0.860	.034	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TYMP–COAD (DFS)

Open the COAD breakdown →