TYMP

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TYMP protein abundance is significantly associated with the RNA expression of many other genes, with 20,339 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TYMP-associated genes across cancer lineages are TNFSF13B, OAS2, and GBP1. Each is linked with TYMP in more than 9 cancer types. Because this analysis shows association rather than direction, both TYMP-to-partner and partner-to-TYMP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TYMP versus TNFSF13B in COAD, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TYMP→partner) and Y-score (partner→TYMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADTNFSF13B →+1.067+0.563<.001<.001310
OVOAS2 →+1.419+0.581<.001<.001310
HNSCGBP1 →+1.608+0.795<.001<.001310
HNSCCD274 →+1.485+0.743<.001<.001310
OVCD80 →+0.868+0.922<.001<.001310
BRCAKLHDC7B →+1.424+0.427<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,339 associations by consensus.

TYMP vs TNFSF13B — COAD

Per-sample scatter of TYMP vs TNFSF13B in COAD (Pearson r = 0.72).

Explore this scatter interactively →

Exploration