TYMP

Across TCGA patient cohorts, TYMP protein abundance is significantly associated with the protein abundance of many other proteins, with 30,262 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TYMP-associated proteins across cancer lineages are IFI35, IFIT2, and IL4I1. Each is linked with TYMP in more than 9 cancer types. Because this analysis shows association rather than direction, both TYMP-to-partner and partner-to-TYMP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TYMP versus IFI35 in GBM, with a Pearson correlation of 0.73.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TYMP→partner) and Y-score (partner→TYMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	IFI35 →	+0.537	+0.922	<.001	<.001	3	10
HNSC	IFIT2 →	+0.878	+0.535	<.001	<.001	3	10
GBM	IL4I1 →	+0.896	+0.836	<.001	<.001	3	10
GBM	NCF4 →	+0.684	+0.835	<.001	<.001	3	10
OV	NMI →	+0.615	+0.645	<.001	<.001	3	10
GBM	OSTF1 →	+0.609	+1.050	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 30,262 associations by consensus.

TYMP vs IFI35 — GBM

Explore this scatter interactively →