TYMP

Across TCGA patient cohorts, TYMP mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TYMP-associated genes across cancer lineages are CD8+ T-cells, Macrophages M1, and CD8+ Tem. Each is linked with TYMP in more than 1 cancer types. Because this analysis shows association rather than direction, both TYMP-to-partner and partner-to-TYMP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by TYMP-low versus TYMP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TYMP→partner) and Y-score (partner→TYMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ T-cells →	+0.023	+3.037	<.001	.003	3	2
UCEC	Macrophages M1 →	+0.022	+2.180	.005	.036	3	2
UCEC	CD8+ Tem →	+0.004	+4.744	<.001	.040	3	1
UCEC	CLP →	-0.067	-3.000	.040	.036	3	1
UCEC	Macrophages M2 →	+0.015	+2.287	.006	.030	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CD8+ T-cells by TYMP expression — UCEC

Explore this box plot interactively →