TXNRD3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TXNRD3 mutation is significantly associated with the RNA expression of many other genes, with 3,752 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TXNRD3-associated genes across cancer lineages are NMBR-AS1, ACTR3P3, and NF1P10. Each is linked with TXNRD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TXNRD3-to-partner and partner-to-TXNRD3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNRD3→partner) and Y-score (partner→TXNRD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCNMBR-AS1 →+0.247+5.612<.001<.00132
SKCMACTR3P3 →+0.038+4.594<.001.00832
CESCNF1P10 →+0.289+4.984<.001.00332
UCECRN7SKP181 →+0.084+2.133.001.00732
UCECRPS15AP27 →+0.072+1.801.002.00732
BRCAOR4M2 →+0.044+8.055<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,752 associations by consensus.

Exploration