Across TCGA patient cohorts, TXNRD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,954 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TXNRD1-associated proteins across cancer lineages are PGD, GCLM, and SMC2. Each is linked with TXNRD1 in more than 7 cancer types. Because this analysis shows association rather than direction, both TXNRD1-to-partner and partner-to-TXNRD1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNRD1→partner) and Y-score (partner→TXNRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PGD →	+0.739	+1.740	<.001	<.001	3	8
LSCC	GCLM →	+0.995	+1.539	<.001	<.001	3	7
LSCC	SMC2 →	+0.489	+1.077	<.001	<.001	3	6
LSCC	SMC4 →	+0.487	+1.229	<.001	<.001	3	6
LSCC	G6PD →	+0.921	+1.858	<.001	<.001	3	6
LSCC	SQSTM1_S272 →	+0.779	+1.123	.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,954 associations by consensus.

Exploration

TXNRD1 survival (RNA) · tumor vs normal (RNA) · all TXNRD1 data types