TXNL1

Across TCGA patient cohorts, TXNL1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,705 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TXNL1-associated genes across cancer lineages are DYM, SMAD4, and MBD2. Each is linked with TXNL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TXNL1-to-partner and partner-to-TXNL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TXNL1 versus DYM in LSCC, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNL1→partner) and Y-score (partner→TXNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DYM →	+0.617	+0.407	<.001	<.001	3	7
LSCC	SMAD4 →	+0.649	+0.404	<.001	<.001	3	7
LSCC	MBD2 →	+0.597	+0.374	<.001	<.001	3	7
LSCC	ELAC1 →	+0.522	+0.342	<.001	<.001	3	6
LSCC	NEDD4L →	+0.944	+0.374	<.001	<.001	3	6
HNSC	VPS4B →	+0.611	+0.193	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,705 associations by consensus.

TXNL1 vs DYM — LSCC

Explore this scatter interactively →