TXNL1

Across TCGA cell cohorts, TXNL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,278 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TXNL1-associated GO terms across cancer lineages are Establishment of meiotic spindle orientation, Negative regulation of mitotic spindle assembly checkpoint signaling, and Left ventricular cardiac muscle tissue morphogenesis. Each is linked with TXNL1 in more than 12 cancer types. Because this analysis shows association rather than direction, both TXNL1-to-partner and partner-to-TXNL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of meiotic spindle orientation grouped by TXNL1-low versus TXNL1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNL1→partner) and Y-score (partner→TXNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Establishment of meiotic spindle orientation →	+0.177	+0.746	<.001	<.001	3	13
KIDNEY	Negative regulation of mitotic spindle assembly checkpoint signaling →	+0.170	+0.715	.002	<.001	3	10
LARGE_INTESTINE	Left ventricular cardiac muscle tissue morphogenesis →	+0.586	+0.631	<.001	<.001	3	10
KIDNEY	Negative regulation of spindle checkpoint →	+0.170	+0.715	.002	<.001	3	10
KIDNEY	Negative regulation of cell cycle checkpoint →	+0.177	+0.807	<.001	.001	3	9
SOFT_TISSUE	Ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway →	+0.141	+0.662	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,278 associations by consensus.

Establishment of meiotic spindle orientation by TXNL1 expression — STOMACH

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