Across TCGA patient cohorts, TXNDC8 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,733 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TXNDC8-associated GO terms across cancer lineages are Negative regulation of proteolysis involved in protein catabolic process, Negative regulation of proteasomal protein catabolic process, and Regulation of organelle assembly. Each is linked with TXNDC8 in more than 12 cancer types. Because this analysis shows association rather than direction, both TXNDC8-to-partner and partner-to-TXNDC8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNDC8→partner) and Y-score (partner→TXNDC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of proteolysis involved in protein catabolic process →	+0.063	+0.183	.001	.002	3	13
ESCA	Negative regulation of proteasomal protein catabolic process →	+0.065	+0.255	<.001	<.001	3	12
STAD	Regulation of organelle assembly →	+0.056	+0.094	<.001	<.001	3	12
STAD	Negative regulation of ubiquitin-dependent protein catabolic process →	+0.062	+0.098	<.001	<.001	3	12
STAD	Cellular response to steroid hormone stimulus →	+0.053	+0.095	<.001	<.001	3	12
STAD	Regulation of proteolysis involved in protein catabolic process →	+0.058	+0.097	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,733 associations by consensus.

Exploration

TXNDC8 survival (RNA) · tumor vs normal (RNA) · all TXNDC8 data types