TXNDC17

Across TCGA patient cohorts, TXNDC17 protein abundance is significantly associated with the RNA expression of many other genes, with 12,111 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TXNDC17-associated genes across cancer lineages are FCGR3B, KIAA0753, and C1QBP. Each is linked with TXNDC17 in more than 4 cancer types. Because this analysis shows association rather than direction, both TXNDC17-to-partner and partner-to-TXNDC17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TXNDC17 versus FCGR3B in UCEC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNDC17→partner) and Y-score (partner→TXNDC17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FCGR3B →	-1.050	-0.331	.008	.001	3	4
OV	KIAA0753 →	+0.580	+0.229	.004	.005	2	5
OV	C1QBP →	+0.742	+0.409	<.001	<.001	3	4
BRCA	TNK1 →	+0.718	+0.257	<.001	.003	2	5
LUAD	EFNA4 →	+0.691	+0.503	<.001	<.001	3	4
CCRCC	PIP5K1B →	-0.713	-0.310	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,111 associations by consensus.

TXNDC17 vs FCGR3B — UCEC

Explore this scatter interactively →