TXNDC17

Across TCGA patient cohorts, TXNDC17 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TXNDC17-associated genes across cancer lineages are MIR7976, SPDYE20P, and OR9Q2. Each is linked with TXNDC17 in more than 1 cancer types. Because this analysis shows association rather than direction, both TXNDC17-to-partner and partner-to-TXNDC17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7976 grouped by TXNDC17-low versus TXNDC17-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNDC17→partner) and Y-score (partner→TXNDC17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7976 →	+0.443	+3.131	.004	.003	3	1
UCEC	SPDYE20P →	+0.315	+4.206	<.001	<.001	3	1
COAD	OR9Q2 →	+0.072	+5.721	<.001	.001	3	1
COAD	OR1F2P →	+0.163	+4.237	<.001	.008	3	1
COAD	MIR147A →	+0.650	+4.893	<.001	.005	3	1
COAD	H3P9 →	+0.316	+4.602	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

MIR7976 by TXNDC17 expression — UCEC

Explore this box plot interactively →