TXNDC17

Across TCGA cell cohorts, TXNDC17 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,238 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible TXNDC17-associated GO terms across cancer lineages are Telomere assembly, Regulation of establishment of protein localization to telomere, and [2Fe-2S] cluster assembly. Each is linked with TXNDC17 in more than 10 cancer types. Because this analysis shows association rather than direction, both TXNDC17-to-partner and partner-to-TXNDC17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere assembly grouped by TXNDC17-low versus TXNDC17-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TXNDC17→partner) and Y-score (partner→TXNDC17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Telomere assembly →	+0.172	+1.252	<.001	<.001	3	11
LUNG_SCLC	Regulation of establishment of protein localization to telomere →	+0.116	+0.825	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	[2Fe-2S] cluster assembly →	+0.123	+0.922	.001	<.001	3	10
SKIN	Cytochrome complex assembly →	+0.075	+0.785	<.001	<.001	3	10
OVARY	Negative regulation of autophagy →	-0.071	-0.929	<.001	<.001	3	9
OVARY	5-phosphoribose 1-diphosphate metabolic process →	+0.147	+0.805	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,238 associations by consensus.

Telomere assembly by TXNDC17 expression — LUNG_SCLC

Explore this box plot interactively →