TXLNGY

Across TCGA pan-cancer cohorts, TXLNGY RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated TXLNGY data layer compared with 1 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TXLNGY RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated TXLNGY expression acts as an unfavorable survival marker, although some lineages such as HNSC and MESO show a favorable association.

HNSC, THCA, and OV are the cancer types where TXLNGY RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.420	0.248	<.001	93	view →
THCA	DFS	Median	All	0.897	0.953	<.001	81	view →
OV	DFS	Tertile	All	0.319	0.396	.025	78	view →
DLBC	OS	Median	All	0.732	1.000	.005	46	view →
MESO	OS	Median	All	0.517	0.277	.001	43	view →
LGG	DFS	Median	All	0.748	0.894	<.001	24	view →
ESCA	DFS	Quartile	All	1.000	0.243	.003	24	view →
UVM	OS	Quartile	III,IV	0.899	0.356	.009	23	view →
LAML	DFS	Quartile	All	0.631	0.266	.013	16	view →
READ	DFS	Quartile	All	0.282	0.712	.018	14	view →
BLCA	OS	Tertile	III,IV	0.426	0.276	.015	13	view →
LUAD	DFS	Tertile	IV	0.909	0.452	.010	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

TXLNGY–HNSC (DFS)

Open the HNSC breakdown →