TXLNB

Across TCGA patient cohorts, TXLNB protein abundance is significantly associated with the RNA expression of many other genes, with 3,783 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TXLNB-associated genes across cancer lineages are SGCA, PDE1B, and FLNC. Each is linked with TXLNB in more than 2 cancer types. Because this analysis shows association rather than direction, both TXLNB-to-partner and partner-to-TXLNB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TXLNB versus SGCA in HNSC, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TXLNB→partner) and Y-score (partner→TXLNB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SGCA →	+1.299	+1.349	<.001	<.001	3	3
UCEC	PDE1B →	+0.463	+0.641	.002	<.001	3	3
UCEC	FLNC →	+1.581	+0.692	<.001	<.001	3	3
HNSC	AOC3 →	+0.926	+1.553	<.001	<.001	3	3
UCEC	RAMP2 →	+0.977	+0.592	<.001	<.001	3	3
UCEC	PGM5 →	+1.429	+0.501	.002	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,783 associations by consensus.

TXLNB vs SGCA — HNSC

Explore this scatter interactively →