TXLNB

Across TCGA pan-cancer cohorts, TXLNB RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated TXLNB data layer compared with 5 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher TXLNB RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TXLNB expression acts as an unfavorable survival marker, although some lineages such as LUAD and SKCM show a favorable association.

BLCA, LUAD, and LGG are the cancer types where TXLNB RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	II,III,IV	0.548	0.737	<.001	88	view →
LUAD	OS	Quartile	II,III,IV	0.749	0.400	<.001	82	view →
LGG	OS	Median	All	0.721	0.895	<.001	50	view →
SKCM	OS	Median	II,III,IV	0.394	0.225	.001	50	view →
BRCA	DFS	Median	IV	0.788	0.329	.002	44	view →
CESC	OS	Tertile	All	0.934	0.805	.003	42	view →
ACC	DFS	Tertile	All	0.836	0.472	<.001	39	view →
HNSC	DFS	Median	IV	0.441	0.294	.002	17	view →
LIHC	OS	Quartile	All	0.699	0.843	.013	13	view →
THYM	DFS	Quartile	All	0.802	0.975	.014	11	view →
UVM	OS	Median	All	0.491	0.853	.010	9	view →
MESO	DFS	Median	III,IV	0.275	0.570	.020	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

TXLNB–BLCA (OS)

Open the BLCA breakdown →