TWSG1

Across TCGA patient cohorts, TWSG1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,371 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TWSG1-associated genes across cancer lineages are CALU, POGLUT2, and FKBP10. Each is linked with TWSG1 in more than 5 cancer types. Because this analysis shows association rather than direction, both TWSG1-to-partner and partner-to-TWSG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TWSG1 versus CALU in BRCA, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TWSG1→partner) and Y-score (partner→TWSG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CALU →	+0.788	+0.418	<.001	<.001	3	6
BRCA	POGLUT2 →	+0.844	+0.535	<.001	<.001	3	5
LUAD	FKBP10 →	+1.247	+0.406	<.001	<.001	3	5
UCEC	EFEMP2 →	+0.820	+0.448	.003	.002	3	5
PDAC	MFAP2 →	+0.784	+0.472	<.001	<.001	3	5
HNSC	GXYLT2 →	+1.152	+0.358	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,371 associations by consensus.

TWSG1 vs CALU — BRCA

Explore this scatter interactively →