TWSG1

Across TCGA patient cohorts, TWSG1 protein abundance is significantly associated with the protein abundance of many other proteins, with 16,603 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TWSG1-associated proteins across cancer lineages are P3H1, P3H4, and PLOD1. Each is linked with TWSG1 in more than 7 cancer types. Because this analysis shows association rather than direction, both TWSG1-to-partner and partner-to-TWSG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TWSG1 versus P3H1 in GBM, with a Pearson correlation of 0.36.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TWSG1→partner) and Y-score (partner→TWSG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	P3H1 →	+0.743	+0.645	<.001	<.001	2	8
LSCC	P3H4 →	+0.687	+0.422	<.001	<.001	2	8
BRCA	PLOD1 →	+0.513	+0.423	<.001	<.001	3	7
BRCA	CRTAP →	+0.584	+0.400	<.001	<.001	3	7
GBM	FKBP10 →	+0.694	+0.803	<.001	<.001	3	7
BRCA	FKBP14 →	+0.634	+0.448	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,603 associations by consensus.

TWSG1 vs P3H1 — GBM

Explore this scatter interactively →