TWF1

Across TCGA cell cohorts, TWF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,261 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TWF1-associated GO terms across cancer lineages are Response to hepatocyte growth factor, Regulation of cell cycle checkpoint, and Cellular response to hepatocyte growth factor stimulus. Each is linked with TWF1 in more than 11 cancer types. Because this analysis shows association rather than direction, both TWF1-to-partner and partner-to-TWF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to hepatocyte growth factor grouped by TWF1-low versus TWF1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TWF1→partner) and Y-score (partner→TWF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Response to hepatocyte growth factor →	+0.145	+1.214	<.001	<.001	3	12
LIVER	Regulation of cell cycle checkpoint →	+0.093	+1.073	.009	.002	3	10
SOFT_TISSUE	Cellular response to hepatocyte growth factor stimulus →	+0.152	+1.215	<.001	<.001	3	10
BLOOD_Lymphoma	Regulation of chromosome segregation →	+0.082	+0.763	.002	.005	3	10
CNS	Nuclear division →	+0.060	+0.859	.001	<.001	3	9
LIVER	Adiponectin-activated signaling pathway →	+0.092	+1.038	.007	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,261 associations by consensus.

Response to hepatocyte growth factor by TWF1 expression — SOFT_TISSUE

Explore this box plot interactively →