TVP23BP1

Across TCGA patient cohorts, TVP23BP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,646 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TVP23BP1-associated GO terms across cancer lineages are Negative regulation of protein localization, Mitochondrial membrane organization, and Protein polymerization. Each is linked with TVP23BP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both TVP23BP1-to-partner and partner-to-TVP23BP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein localization grouped by TVP23BP1-low versus TVP23BP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TVP23BP1→partner) and Y-score (partner→TVP23BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of protein localization →	+0.089	+0.063	<.001	<.001	3	10
STAD	Mitochondrial membrane organization →	+0.107	+0.066	<.001	<.001	3	9
STAD	Protein polymerization →	+0.089	+0.066	<.001	<.001	3	9
STAD	Regulation of protein serine/threonine kinase activity →	+0.084	+0.062	<.001	<.001	3	9
STAD	Mitochondrial fusion →	+0.091	+0.068	<.001	<.001	3	9
STAD	Peptidyl-lysine modification →	+0.094	+0.074	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,646 associations by consensus.

Negative regulation of protein localization by TVP23BP1 expression — STAD

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