TVP23BP1

Across TCGA pan-cancer cohorts, TVP23BP1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of TVP23BP1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where TVP23BP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TVP23BP1 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

THCA, PRAD, and KIRC are the cancer types where TVP23BP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TVP23BP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	+0.034	.029	4	view →
PRAD	All	All	+0.015	.032	2	view →
KIRC	All	II,III,IV	−0.008	.042	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

TVP23BP1–THCA

Open the THCA breakdown →