TVP23B

Across TCGA patient cohorts, TVP23B RNA expression is significantly associated with the go_rna of many other GO terms, with 7,164 significant associations in total. THYM shows the largest number of these associations.

The most reproducible TVP23B-associated GO terms across cancer lineages are Regulation of centriole replication, snRNA transport, and COPII-coated vesicle cargo loading. Each is linked with TVP23B in more than 29 cancer types. Because this analysis shows association rather than direction, both TVP23B-to-partner and partner-to-TVP23B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centriole replication grouped by TVP23B-low versus TVP23B-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TVP23B→partner) and Y-score (partner→TVP23B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Regulation of centriole replication →	+0.078	+0.725	<.001	<.001	3	30
SCLC	snRNA transport →	+0.146	+0.717	<.001	<.001	3	30
DLBC	COPII-coated vesicle cargo loading →	+0.104	+0.790	<.001	<.001	3	30
UVM	Membrane fission →	+0.072	+1.039	<.001	<.001	3	30
CHOL	Postreplication repair →	+0.055	+0.920	.004	<.001	3	30
SCLC	Positive regulation of mRNA 3'-end processing →	+0.114	+0.597	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,164 associations by consensus.

Regulation of centriole replication by TVP23B expression — DLBC

Explore this box plot interactively →