TUT7

Across TCGA pan-cancer cohorts, TUT7 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TUT7 data layer compared with 24 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TUT7 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated TUT7 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LUAD show a favorable association.

UCEC, LUAD, and PDAC are the cancer types where TUT7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	1.000	0.898	.004	28	view →
LUAD	DFS	Tertile	All	0.961	0.824	.006	19	view →
PDAC	DFS	Median	II,III,IV	0.925	0.613	.001	13	view →
HNSC	DFS	Median	II,III,IV	0.976	0.897	.036	8	view →
GBM	DFS	Median	All	0.297	0.448	.032	4	view →
CCRCC	DFS	Median	All	0.831	0.597	.034	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TUT7–UCEC (OS)

Open the UCEC breakdown →