TUT7

Across TCGA pan-cancer cohorts, TUT7 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of TUT7’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where TUT7 RNA is repressed in tumor relative to normal tissue. In most cancer types TUT7 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KIRC, and HNSC are the cancer types where TUT7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TUT7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	II,III,IV	−0.514	<.001	8	view →
KIRC	All	All	+0.423	<.001	7	view →
HNSC	All	All	+0.333	.025	3	view →
PRAD	All	All	+1.080	<.001	2	view →
LUSC	Male	All	+0.355	.004	2	view →
KICH	All	All	−0.533	.012	1	view →
KIRP	All	II,III,IV	+0.446	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

TUT7–THCA

Open the THCA breakdown →