TUT7

Across TCGA patient cohorts, TUT7 mutation is significantly associated with the RNA expression of many other genes, with 2,553 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUT7-associated genes across cancer lineages are WARS1, PNPLA3, and SLF1. Each is linked with TUT7 in more than 3 cancer types. Because this analysis shows association rather than direction, both TUT7-to-partner and partner-to-TUT7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WARS1 grouped by TUT7-low versus TUT7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUT7→partner) and Y-score (partner→TUT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	WARS1 →	+0.566	+2.209	<.001	<.001	3	4
COAD	PNPLA3 →	+0.982	+3.472	<.001	.002	3	3
COAD	SLF1 →	+0.471	+3.472	.002	.002	3	3
SKCM	SLC25A15P4 →	+0.632	+3.877	.004	.004	3	3
UCEC	ME2 →	+0.411	+1.332	<.001	.003	3	3
BLCA	RPS14P5 →	+0.134	+2.336	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,553 associations by consensus.

WARS1 by TUT7 expression — UCEC

Explore this box plot interactively →