TUT7

Across TCGA cell cohorts, TUT7 mutation is significantly associated with the RNA expression of many other genes, with 906 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TUT7-associated genes across cancer lineages are TAS2R8, OR6P1, and MTRNR2L10. Each is linked with TUT7 in more than 1 cancer types. Because this analysis shows association rather than direction, both TUT7-to-partner and partner-to-TUT7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAS2R8 grouped by TUT7-low versus TUT7-high in KIDNEY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUT7→partner) and Y-score (partner→TUT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	TAS2R8 →	+0.030	+5.000	<.001	.005	3	1
KIDNEY	OR6P1 →	+0.013	+5.000	<.001	.005	3	1
KIDNEY	MTRNR2L10 →	+0.013	+5.000	<.001	.005	3	1
BLOOD_Leukemia	ALLC →	+0.079	+3.714	<.001	.005	3	1
BLOOD_Leukemia	OR51T1 →	+0.052	+3.922	<.001	.002	3	1
BLOOD_Leukemia	SAMD7 →	+0.125	+4.022	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 906 associations by consensus.

TAS2R8 by TUT7 expression — KIDNEY

Explore this box plot interactively →