Across TCGA patient cohorts, TUSC1 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. CESC shows the largest number of these associations.

The most reproducible TUSC1-associated genes across cancer lineages are RPL30P5, OR2A15P, and LINC01568. Each is linked with TUSC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TUSC1-to-partner and partner-to-TUSC1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUSC1→partner) and Y-score (partner→TUSC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RPL30P5 →	+0.133	+5.345	<.001	.001	3	1
CESC	OR2A15P →	+0.059	+4.760	<.001	.003	3	1
CESC	LINC01568 →	+0.015	+4.653	.001	.004	3	1
CESC	MIR6806 →	+0.967	+4.409	<.001	.006	3	1
CESC	DEFB127 →	+0.072	+5.342	<.001	.002	3	1
LIHC	RNU6-967P →	+0.440	+6.149	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

TUSC1 survival (RNA) · tumor vs normal (RNA) · all TUSC1 data types