TUBGCP5

Across TCGA patient cohorts, TUBGCP5 mutation is significantly associated with the RNA expression of many other genes, with 3,329 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBGCP5-associated genes across cancer lineages are RNU6-771P, RPL31P59, and RN7SL134P. Each is linked with TUBGCP5 in more than 2 cancer types. Because this analysis shows association rather than direction, both TUBGCP5-to-partner and partner-to-TUBGCP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-771P grouped by TUBGCP5-low versus TUBGCP5-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBGCP5→partner) and Y-score (partner→TUBGCP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-771P →	+0.228	+7.930	<.001	.008	3	3
READ	RPL31P59 →	+0.129	+4.421	<.001	.009	3	3
UCEC	RN7SL134P →	+0.074	+1.682	.002	.002	3	3
BRCA	MIR6754 →	+0.412	+4.298	<.001	.009	3	2
CESC	LINC02559 →	+1.780	+6.342	<.001	.001	3	2
CESC	MIR8053 →	+0.486	+6.342	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,329 associations by consensus.

RNU6-771P by TUBGCP5 expression — LUAD

Explore this box plot interactively →