TUBGCP5

Across TCGA pan-cancer cohorts, TUBGCP5 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of TUBGCP5’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where TUBGCP5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TUBGCP5 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

HNSC, THCA, and LIHC are the cancer types where TUBGCP5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TUBGCP5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.645	<.001	12	view →
THCA	All	II,III,IV	−0.620	<.001	10	view →
LIHC	All	III,IV	+0.786	<.001	9	view →
LUSC	Male	All	+0.591	<.001	6	view →
COAD	Female	All	+0.555	<.001	6	view →
BLCA	All	All	+0.444	.005	6	view →
CHOL	Male	All	+1.323	<.001	5	view →
READ	All	II,III,IV	+0.649	.002	4	view →
LUAD	All	All	+0.305	<.001	4	view →
KIRP	Female	II,III,IV	+0.466	.025	2	view →
KICH	All	All	−0.336	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

TUBGCP5–HNSC

Open the HNSC breakdown →