TUBGCP5

Across TCGA patient cohorts, TUBGCP5 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBGCP5-associated genes across cancer lineages are Caspase-7-cleavedD198, 14-3-3_beta, and Ku80. Each is linked with TUBGCP5 in more than 2 cancer types. Because this analysis shows association rather than direction, both TUBGCP5-to-partner and partner-to-TUBGCP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by TUBGCP5-low versus TUBGCP5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBGCP5→partner) and Y-score (partner→TUBGCP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.556	+2.157	.001	<.001	3	3
UCEC	14-3-3_beta →	-0.092	-1.973	.001	.002	3	2
UCEC	Ku80 →	+0.242	+1.549	<.001	.001	3	2
UCEC	PDCD4 →	-0.337	-0.999	.012	.042	3	2
UCEC	STAT3_pY705 →	-0.244	-1.279	.001	.021	3	2
UCEC	ASNS →	+0.301	+1.321	.003	.027	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Caspase-7-cleavedD198 by TUBGCP5 expression — UCEC

Explore this box plot interactively →