TUBGCP5

Across TCGA cell cohorts, TUBGCP5 mutation is significantly associated with the RNA expression of many other genes, with 304 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TUBGCP5-associated genes across cancer lineages are ALKBH7, PKNOX1, and PTH. Each is linked with TUBGCP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBGCP5-to-partner and partner-to-TUBGCP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ALKBH7 grouped by TUBGCP5-low versus TUBGCP5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBGCP5→partner) and Y-score (partner→TUBGCP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ALKBH7 →	+0.412	+3.364	.009	.002	3	2
LARGE_INTESTINE	PKNOX1 →	+0.607	+3.087	.001	.006	3	2
BLOOD_Lymphoma	PTH →	+0.009	+3.925	<.001	.006	3	1
BLOOD_Lymphoma	EMX2 →	+0.028	+3.876	<.001	.003	3	1
BLOOD_Lymphoma	CPA1 →	+0.025	+2.874	.001	.009	3	1
SKIN	FEV →	+0.125	+3.823	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 304 associations by consensus.

ALKBH7 by TUBGCP5 expression — LARGE_INTESTINE

Explore this box plot interactively →