TUBGCP3

Across TCGA cell cohorts, TUBGCP3 mutation is significantly associated with the RNA expression of many other genes, with 498 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TUBGCP3-associated genes across cancer lineages are MBD3L2, USP29, and OTOS. Each is linked with TUBGCP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBGCP3-to-partner and partner-to-TUBGCP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MBD3L2 grouped by TUBGCP3-low versus TUBGCP3-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBGCP3→partner) and Y-score (partner→TUBGCP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	MBD3L2 →	+0.151	+5.228	<.001	.005	3	1
BLOOD_Leukemia	USP29 →	+0.007	+5.507	<.001	<.001	3	1
BLOOD_Leukemia	OTOS →	+0.039	+4.969	<.001	.003	3	1
BLOOD_Leukemia	KRTAP10-2 →	+0.131	+4.152	<.001	.009	3	1
BLOOD_Leukemia	KRTAP12-2 →	+0.072	+4.969	<.001	.003	3	1
BLOOD_Leukemia	OR5M1 →	+0.015	+5.569	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 498 associations by consensus.

MBD3L2 by TUBGCP3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →