TUBGCP2

Across TCGA cell cohorts, TUBGCP2 mutation is significantly associated with the mutation status of many other genes, with 4,849 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TUBGCP2-associated genes across cancer lineages are PCDH1, ABCA1, and SVIL. Each is linked with TUBGCP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both TUBGCP2-to-partner and partner-to-TUBGCP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCDH1 grouped by TUBGCP2-low versus TUBGCP2-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBGCP2→partner) and Y-score (partner→TUBGCP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	PCDH1 →	+5.614	+5.044	.003	.003	1	5
LARGE_INTESTINE	ABCA1 →	+1.681	+2.228	<.001	<.001	1	5
LARGE_INTESTINE	SVIL →	+1.485	+2.321	<.001	<.001	1	5
CNS	ADGRB2 →	+4.614	+5.584	<.001	<.001	1	4
LUNG_NSCLC_LUAD	LIMCH1 →	+3.117	+4.491	.004	.004	1	4
BLOOD_Lymphoma	PACS1 →	+5.554	+4.584	<.001	<.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,849 associations by consensus.

PCDH1 by TUBGCP2 expression — CNS

Explore this box plot interactively →