TUBG2

Across TCGA pan-cancer cohorts, TUBG2 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TUBG2 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TUBG2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TUBG2 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

UCEC, LUAD, and LSCC are the cancer types where TUBG2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	0.339	1.000	.004	16	view →
LUAD	DFS	Median	All	1.000	0.885	.013	10	view →
LSCC	DFS	Tertile	II,III,IV	0.666	0.866	.047	1	view →
CCRCC	OS	Median	All	1.000	0.651	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TUBG2–UCEC (OS)

Open the UCEC breakdown →