TUBD1

Across TCGA cell cohorts, TUBD1 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TUBD1-associated genes across cancer lineages are GNG8, OR1L6, and WFDC6. Each is linked with TUBD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBD1-to-partner and partner-to-TUBD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GNG8 grouped by TUBD1-low versus TUBD1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBD1→partner) and Y-score (partner→TUBD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GNG8 →	+0.479	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR1L6 →	+0.019	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	WFDC6 →	+0.050	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	C1orf232 →	+0.047	+4.887	<.001	.009	3	1
LARGE_INTESTINE	OR14K1 →	+0.068	+4.022	<.001	.006	3	1
LARGE_INTESTINE	KRTAP10-2 →	+0.065	+3.994	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

GNG8 by TUBD1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →