TUBBP5

Across TCGA patient cohorts, TUBBP5 mutation is significantly associated with the RNA expression of many other genes, with 613 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBBP5-associated genes across cancer lineages are RNA5SP413, MRPS21P5, and NDUFS6P1. Each is linked with TUBBP5 in more than 3 cancer types. Because this analysis shows association rather than direction, both TUBBP5-to-partner and partner-to-TUBBP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP413 grouped by TUBBP5-low versus TUBBP5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBBP5→partner) and Y-score (partner→TUBBP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP413 →	+0.846	+1.746	<.001	.006	3	4
COAD	MRPS21P5 →	+0.268	+4.308	.002	.009	3	2
COAD	NDUFS6P1 →	+0.222	+5.136	<.001	.002	3	2
UCEC	ASB6 →	+0.390	+3.627	<.001	.001	3	2
LGG	RN7SL228P →	+0.128	+7.977	<.001	.007	3	2
CESC	DNAJA1P1 →	+0.035	+4.306	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 613 associations by consensus.

RNA5SP413 by TUBBP5 expression — UCEC

Explore this box plot interactively →