Q-omics provides the consensus-scored TUBBP2 profile across patient tissues and cancer cell-line models. TUBBP2 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, TUBBP2 is differentially expressed in 9, with the highest sampling consensus in HNSC. Additionally, TUBBP2 RNA expression shows 8,986 significant protein co-abundance associations, with the highest sampling consensus in BRCA. Together, these results highlight ACC, HNSC, and BRCA as cancer lineages where TUBBP2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TUBBP2 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TUBBP2 survival associations across molecular data types. TUBBP2 RNA expression shows survival associations in the most cancer types (24). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TUBBP2 RNA expression–survival associations across cancer types. High TUBBP2 expression shows unfavorable associations in ACC, PAAD, KICH and STAD, but favorable associations in THCA and THYM. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for TUBBP2 RNA expression.
This table summarizes TUBBP2 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for TUBBP2. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TUBBP2 shows higher tumor expression in HNSC, LUSC, KIRP, KIRC, BRCA and STAD. The HNSC box plot shows higher TUBBP2 RNA expression in tumor versus normal tissue (log2 FC = +0.322, t-test p < 0.001).
This table shows molecular features associated with TUBBP2 in patient tissues and cancer cell lines. In patient samples, TUBBP2 shows the broadest associations at the RNA and protein expression levels, with BRCA recurring as the lineage with the largest associated feature set.
