tubulin beta 8 class VIII pseudogene 8Genealiases: []
Q-omics provides the consensus-scored TUBB8P8 profile across patient tissues and cancer cell-line models. TUBB8P8 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in UCS. Among the 18 cancer types available for tumor–normal comparison, TUBB8P8 is differentially expressed in 6, with the highest sampling consensus in HNSC. Additionally, TUBB8P8 RNA expression shows 12,847 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight UCS, HNSC, and THYM as cancer lineages where TUBB8P8 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TUBB8P8 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TUBB8P8 survival associations across molecular data types. TUBB8P8 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TUBB8P8 RNA expression–survival associations across cancer types. High TUBB8P8 expression shows unfavorable associations in UCS, ACC, UVM, STAD and SKCM, but favorable associations in CESC. The UCS Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify UCS as the clearest survival context for TUBB8P8 RNA expression.
This table summarizes TUBB8P8 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for TUBB8P8. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TUBB8P8 shows lower tumor expression in PAAD and higher tumor expression in HNSC, BRCA, BLCA, LUSC and THCA. The HNSC box plot shows higher TUBB8P8 RNA expression in tumor versus normal tissue (log2 FC = +0.114, t-test p < 0.001).
This table shows molecular features associated with TUBB8P8 in patient tissues and cancer cell lines. In patient samples, TUBB8P8 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
